Symphogen (Denmark)

Recent papers from Symphogen (Denmark)

1. Automated Multienzyme Digestion Workflows for Confident Characterization of Challenging Posttranslational Modifications in Therapeutic Antibodies by LC–MS/MSRapid Communications in Mass Spectrometry · 2026
2. A cell-based kinetic framework enables TCR specificity predictionSignal Transduction and Targeted Therapy · 2026
3. Phase Ib multicenter study of anti-TIM-3 (S095018/Sym023) in combination with anti-PD-1 (Sym021) in patients with advanced/metastatic recurrent biliary tract cancerJournal for ImmunoTherapy of Cancer · 2026
4. Therapeutic Lymphangiogenesis Using Induced Cardiac Fibroblasts Protects the Heart From Heart Failure With Preserved Ejection Fraction Progression by Exerting Anti-Inflammatory and Antifibrotic EffectsCirculation Journal · 2026
5. Rapid and selective characterization of antibody-drug conjugates in complex sample matrices by native affinity liquid chromatography-mass spectrometry.2026
6. The AML cellular state space unveils NPM1 immune evasion subtypes with distinct clinical outcomesNature Communications · 2025
7. Tricked by Edge Cases: Can Current Approaches Lead to Accurate Prediction of T-Cell Specificity with Machine Learning?2024
8. Endomucin marks quiescent long-term multi-lineage repopulating hematopoietic stem cells and is essential for their transendothelial migrationCell Reports · 2024
9. Addressing Acid-Catalyzed Deamidation and the Solubility of Hydrophobic Peptides in Multi-Attribute Method WorkflowsAnalytical Chemistry · 2023
10. Discovery of neutralizing SARS-CoV-2 antibodies enriched in a unique antigen specific B cell clusterPLoS ONE · 2023
11. Surfaceome analyses uncover CD98hc as an antibody drug-conjugate target in triple negative breast cancerJournal of Experimental & Clinical Cancer Research · 2022
12. Generation of Antibody-Drug Conjugate Resistant ModelsCancers · 2021
13. Deep neural networks identify signaling mechanisms of ErbB-family drug resistance from a continuous cell morphology spaceCell Reports · 2021
14. Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasisScientific Reports · 2020
15. Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotypeScience Translational Medicine · 2020
16. Inter-laboratory study of an optimised peptide mapping workflow using automated trypsin digestion for monitoring monoclonal antibody product quality attributesAnalytical and Bioanalytical Chemistry · 2020
17. Simultaneous targeting of HER family pro-survival signaling with Pan-HER antibody mixture is highly effective in TNBC: a preclinical trial with PDXsBreast Cancer Research · 2020
18. Relationship Between Response and Dose in Published, Contemporary Phase I Oncology TrialsJournal of the National Comprehensive Cancer Network · 2020
19. Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradationScientific Reports · 2020
20. HER-Family Ligands Promote Acquired Resistance to Trastuzumab in Gastric CancerMolecular Cancer Therapeutics · 2019