Arrien Pharmaceuticals (United States)

Recent papers from Arrien Pharmaceuticals (United States)

1. Practically Significant Method Comparison Protocols for Machine Learning in Small Molecule Drug DiscoveryJournal of Chemical Information and Modeling · 2025
2. Assessing individual head and neck squamous cell carcinoma patient response to therapy through integration of functional and genomic dataScientific Reports · 2025
3. Sustained Accumulation of Molecular Clock Suppressors Period 1 and Period 2 Promotes C2C12 Myotube Atrophy Through an Autocrine-Mediated Mechanism With Relevance to Androgen Deprivation-Induced Limb Muscle Mass LossFunction · 2025
4. Colocalization of Cancer-Associated Biomarkers on Single Extracellular Vesicles for Early Detection of CancerJournal of Molecular Diagnostics · 2024
5. Clinical pharmacology and tolerability of REC‐994, a redox‐cycling nitroxide compound, in randomized phase 1 dose‐finding studiesPharmacology Research & Perspectives · 2024
6. Abstract 7133: Phenomics-enabled discovery and optimization of small-molecule RBM39 degraders as an alternative to CDK12 targeting in high-grade serous ovarian cancer (HGSOC)Cancer Research · 2024
7. Abstract 6600: Investigating molecular regulators of a dual identity state in lung adenocarcinomaCancer Research · 2024
8. A deep profile of gene expression across 18 human cancers2024
9. Development of a Practical Nomogram for Personalized Anemia Management in Patients Treated with Ataxia Telangiectasia and Rad3-related Inhibitor CamonsertibClinical Cancer Research · 2023
10. A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticidesNature Communications · 2023
11. PAUSE: principled feature attribution for unsupervised gene expression analysisGenome biology · 2023
12. Supplementary Data 3 from Discovery of JNJ-63576253, a Next-Generation Androgen Receptor Antagonist Active Against Wild-Type and Clinically Relevant Ligand Binding Domain Mutations in Metastatic Castration-Resistant Prostate Cancer2023
13. Elephant TP53-RETROGENE 9 induces transcription-independent apoptosis at the mitochondriaCell Death Discovery · 2023
14. Colocalization of Cancer Associated Biomarkers on Single Extracellular Vesicles for Early Cancer Detection2023
15. Chemoinformatics and artificial intelligence colloquium: progress and challenges in developing bioactive compoundsJournal of Cheminformatics · 2022
16. The hypothalamic RFamide, QRFP, increases feeding and locomotor activity: The role of Gpr103 and orexin receptorsPLoS ONE · 2022
17. SIK2 inhibition enhances PARP inhibitor activity synergistically in ovarian and triple-negative breast cancersJournal of Clinical Investigation · 2022
18. Emerging Role of Translational Digital Biomarkers Within Home Cage Monitoring Technologies in Preclinical Drug Discovery and DevelopmentFrontiers in Behavioral Neuroscience · 2022
19. Coupling comprehensive pesticide-wide association study to iPSC dopaminergic screening identifies and classifies Parkinson-relevant pesticides2022
20. Unified AI framework to uncover deep interrelationships between gene expression and Alzheimer’s disease neuropathologiesNature Communications · 2021