Aeterna Zentaris (Germany)

Recent papers from Aeterna Zentaris (Germany)

1. PEGylated Recombinant Aplysia punctata Ink Toxin Depletes Arginine and Lysine and Inhibits the Growth of Tumor XenograftsACS Biomaterials Science & Engineering · 2024
2. Assessment of the Diagnostic Performance of Fully Automated Hepatitis E Virus (HEV) Antibody TestsDiagnostics · 2024
3. Diagnostic performance of a fully automated hepatitis E virus antibody immunoassay2023
4. Diagnostic performance of a fully automated hepatitis E virus antibody immunoassay2023
5. Pilot clinical trial of macimorelin to assess safety and efficacy in patients with cancer cachexiaJournal of Cachexia Sarcopenia and Muscle · 2023
6. PEGylated recombinant Aplysia punctata ink toxin depletes arginine and lysine and inhibits growth of tumor xenografts2023
7. Translational potential of the ghrelin receptor agonist macimorelin for seizure suppression in pharmacoresistant epilepsyEuropean Journal of Neurology · 2021
8. Effects of oral macimorelin on copeptin and anterior pituitary hormones in healthy volunteersPituitary · 2021
9. Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Macimorelin in Children with Suspected Growth Hormone Deficiency: An Open-Label, Group Comparison, Dose-Escalation TrialHormone Research in Paediatrics · 2021
10. Sensitivity and specificity of the macimorelin test for diagnosis of AGHDEndocrine Connections · 2020
11. Safety, tolerability, pharmacokinetics, and pharmacodynamics of macimorelin in healthy adults: Results of a single-dose, randomized controlled studyGrowth Hormone & IGF Research · 2020
12. Macimorelin as a Diagnostic Test for Adult GH DeficiencyThe Journal of Clinical Endocrinology & Metabolism · 2018
13. Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancerJournal of Hematology & Oncology · 2017
14. Efficient synthesis of novel disubstituted pyrido[3,4-b]pyrazines for the design of protein kinase inhibitorsMedChemComm · 2015
15. Abstract 3711: Erk inhibition as a therapeutic option for the treatment of Raf- and Mek- inhibitor resistant tumorsCancer Research · 2014
16. Discovery of 7‐Aryl‐Substituted (1,5‐Naphthyridin‐4‐yl)ureas as Aurora Kinase InhibitorsChemMedChem · 2013
17. Abstract 5476: LHRH receptor targeting as mechanism of anti-tumor activity for cytotoxic conjugates of Disorazol Z with the LHRH receptor agonistic peptide D-Lys6-LHRH.Cancer Research · 2013
18. Abstract 2877: Perifosine alone and in combination with antimetabolites interferes with NF-kB pathway activation in colon cancer cell linesCancer Research · 2012
19. Abstract 871: Dual inhibition of PI3K and Erk1/2 shows synergy and efficacy in human tumor cells, either by using drug combinations or novel dual PI3K/Erk inhibitorsCancer Research · 2012
20. A phase I trial of AEZS-108 (AN-152) in castration- and taxane-resistant prostate cancer.Journal of Clinical Oncology · 2012