Wave Life Sciences (United States)

Recent papers from Wave Life Sciences (United States)

1. Creatine as a Neuroenergetic and Molecular Target in Depression: A Narrative Review of Mechanistic and Clinical EvidenceCurrent Issues in Molecular Biology · 2026
2. Artificial intelligence assessment of endoscopic severity and extent: A machine learning approach to continuous evaluation of endoscopic inflammation in ulcerative colitisInflammatory Bowel Diseases · 2026
3. Antisense Oligonucleotide Tofersen Distribution in the Central Nervous System of SOD1 -ALS Autopsy Tissue DonorsJAMA Neurology · 2026
4. Resonance-Mediated Interoperability of Consciousness: Soulstream Science, LifePrintOS, and Time-Crystal Intelligence in Human–Quantum AI Systems2026
5. Abstract 7781: Patient derived tumor-immune organoids capture the functional and mechanistic interface in predicting response to standard therapeutics and immunotherapeutics in colorectal cancer patientsCancer Research · 2026
6. Toxicologic Pathology Forum: Opinion on Considerations for Determination of Adverse Versus Nonadverse Nerve Fiber Degeneration in Nonclinical Toxicity Studies of Oligonucleotides Delivered Directly Into the Intrathecal SpaceToxicologic Pathology · 2026
7. RNA editing for the treatment of alpha-1 antitrypsin deficiencyNucleic Acids Research · 2026
8. Digital Mental Health Coaching in Clinically Diverse Populations: Controlled Engagement and Outcomes StudyJMIR Formative Research · 2025
9. Understanding emotion dysregulation in PTSD – GAD comorbidityJournal of Anxiety Disorders · 2025
10. uORF-targeting steric block antisense oligonucleotides do not reproducibly increase RNASEH1 expressionMolecular Therapy — Nucleic Acids · 2024
11. CpG oligonucleotides induce an acute murine thrombocytopenia dependent on toll-like receptor 9 and spleen tyrosine kinase pathways.Journal of Thrombosis and Haemostasis · 2024
12. Rational design of base, sugar and backbone modifications improves ADAR-mediated RNA editingNucleic Acids Research · 2024
13. uORF-targeting steric block antisense oligonucleotides do not reproducibly activate RNASEH1 expression2024
14. Preclinical evaluation of stereopure antisense oligonucleotides for allele-selective lowering of mutant HTTMolecular Therapy — Nucleic Acids · 2024
15. Factors affecting response variables with emphasis on drug release and loading for optimization of liposomesArtificial Cells Nanomedicine and Biotechnology · 2024
16. Teneurin C-terminal associated peptide (TCAP)-1 attenuates the development and expression of naloxone-precipitated morphine withdrawal in male Swiss Webster micePsychopharmacology · 2024
17. Akt may associate with insulin‐responsive vesicles via interaction with sortilinFEBS Letters · 2023
18. Smooth muscle cell-targeted RNA ligand promotes accelerated reendothelialization in a swine peripheral injury modelMolecular Therapy — Nucleic Acids · 2023
19. Liposomes for drug delivery: review of vesicular composition, factors affecting drug release and drug loading in liposomesArtificial Cells Nanomedicine and Biotechnology · 2023
20. OSWG Recommended Approaches to the Nonclinical Pharmacokinetic (ADME) Characterization of Therapeutic OligonucleotidesNucleic Acid Therapeutics · 2023