Concept Life Sciences (United Kingdom)

Recent papers from Concept Life Sciences (United Kingdom)

1. A general strategy towards multicolour fluorogenic peptides for wash-free bioassaysNature Chemistry · 2026
2. 21P Scalable translational research: A novel extraction free whole transcriptome analyses approach specifically for low quality FFPE diagnostic samples which failed QC for standard NGS analyses in a TNBC cohort (VISION study)ESMO Open · 2026
3. Expedient Synthesis of 1‐Oxo‐1,2,3,4‐Tetrahydroisoquinoline‐4‐CarboxylatesEuropean Journal of Organic Chemistry · 2025
4. B(C₆F₅)₃-Catalyzed Coupling of N-Alkyl Arylamines and Alkenes for the Synthesis of TetrahydroquinolinesOrganic Letters · 2025
5. Expedient Synthesis of 1-Oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylates2025
6. An Immunomodulating Peptide with Potential to Promote Anticancer Immunity Without Compromising Immune ToleranceBiomedicines · 2025
7. Fecal microbiota transplantation as a therapeutic modality for recurrent Clostridioides difficile infection: reviewing efficacy, safety, mechanisms of action, and outcomesAnnals of Medicine and Surgery · 2025
8. Depleting the Action of EZH2 through PI3K–mTOR Inhibition to Overcome Metastasis and Immunotherapy Resistance in Triple-Negative Breast CancerMolecular Cancer Therapeutics · 2025
9. 2-Hydroxypropyl-β-cyclodextrin, solubiliser in a novel dantrolene formulation: Its binding affinities to clinical compounds that may be used during anaesthesia or management of malignant hyperthermiaEuropean Journal of Pharmaceutics and Biopharmaceutics · 2025
10. Optimization of Cyclophilin B-Targeted Tri-vector Inhibitors for Novel MASH TreatmentsJournal of Medicinal Chemistry · 2025
11. Process Development for the Manufacture of a Topical Pan-Trk Inhibitor Incorporating Decarboxylative sp²–sp³ Cross-CouplingOrganic Process Research & Development · 2024
12. A novel immunomodulating peptide with potential to complement oligodeoxynucleotide-mediated adjuvanticity in vaccination strategiesScientific Reports · 2024
13. A handbook for Rhythmic Relating in autism: supporting social timing in play, learning and therapyFrontiers in Psychology · 2024
14. Positive behaviour supports in disability and community services (PBS-DCS): a tiered model for foundational, targeted, and specialist supportsDisability and Rehabilitation · 2024
15. Constitutive activity of ionotropic glutamate receptors via hydrophobic substitutions in the ligand-binding domainStructure · 2024
16. Development of a Safe and Scalable Method to Prepare 3-Bromo-N-alkyl-1,6-naphthyridones via Enamine CyclizationOrganic Process Research & Development · 2024
17. Nonperturbative Fluorogenic Labeling of Immunophilins Enables the Wash-free Detection of ImmunosuppressantsACS Central Science · 2024
18. Transition-Metal-Free Synthesis of a Densely Functionalized Benzodioxole Intermediate toward LotiglipronOrganic Process Research & Development · 2024
19. Accelerating BRPF1b hit identification with BioPhysical and Active Learning Screening (BioPALS)ChemMedChem · 2024
20. Development of a selective and scalable N 1-indazole alkylationRSC Advances · 2024