September 21, 2013Open Access

Right Ventricular Diastolic Impairment in Patients With Pulmonary Arterial Hypertension

Structured PICO

Population

Patients with pulmonary arterial hypertension (PAH)

Outcome

Right ventricular (RV) diastolic stiffnesssurrogate

Increased RV diastolic stiffness in PAH patients is multifactorial, involving both extracellular (collagen) and cellular (sarcomere) mechanisms.

Abstract

RV diastolic stiffness is significantly increased in PAH patients, with important contributions from increased collagen and intrinsic stiffening of the RV cardiomyocyte sarcomeres.

Read Full Paperexternally

Bookmark

View Full Paper

Cite This Study

Rain et al. (Sat,) studied this question.

synapsesocial.com/papers/69d71fd13f906f6a06bef266 https://doi.org/https://doi.org/10.1161/circulationaha.113.001873

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1NT-proBNP reflects right ventricular structure and function in pulmonary hypertension2006 · 95 citations
2Effects of exercise training in patients with idiopathic pulmonary arterial hypertension2009 · 232 citations
3Snapshots of Hemodynamics: An Aid for Clinical Research and Graduate Education2018 · 207 citations
4Estimation of the Hydromotive Source Pressure from Ejecting Beats of the Left Ventricle1980 · 177 citations
5Single-beat estimation of end-diastolic pressure-volume relationship: a novel method with potential for noninvasive application2006 · 298 citations

Bookmark

View Full Paper