Population
Patients with pulmonary arterial hypertension (PAH)
Design
Other
Authors
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May guide RV-targeted therapies in PAH; leaves open whether collagen and sarcomere mechanisms are modifiable.
Increased RV diastolic stiffness in PAH patients is multifactorial, involving both extracellular (collagen) and cellular (sarcomere) mechanisms.
Rain et al. (2013) studied this question.
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