Immuno-PET/CT Imaging of Trop2 Expression with 18 FAlF-RESCA-RT4 Enhances Diagnosis of Breast Cancers and the Metastases

Key Points

• The aim is to evaluate Trop2 expression across different molecular subtypes of breast cancer and assess the efficacy of a new imaging tracer.
• Evaluated Trop2 expression using a novel tracer, [¹⁸F]AlF-RESCA-RT4.
• Performed imaging across various molecular subtypes of breast cancer.
• Compared diagnostic performance against standard imaging techniques.
• Trop2 expression was higher in aggressive subtypes, indicating a potential diagnostic marker.
• The novel tracer provided enhanced imaging clarity compared to traditional methods.
• Significant improvement in diagnosis of metastases was observed, enhancing treatment planning.