Technological advances in acupoint thread embedding treatment: Effects on NIHSS score, Serum SIRT1, HIF-1α, and macrophage efferocytosis in stroke patients

Background Acupoint thread embedding treatment (ATET) is a traditional therapeutic approach used in stroke rehabilitation. Objective To explore the application of ATET in combination with modern medical technology, examining its effects on neurological function and key serum biomarkers in stroke patients. Methods A total of 108 stroke patients were randomly assigned to ATE treatment group (n = 52) and Control Group (n = 56). Various parameters including baseline characteristics, levels of inflammatory markers, macrophage efferocytosis-related factors, the National Institutes of Health Stroke Scale (NIHSS) scores, therapeutic efficacy, and adverse events were assessed and compared between the two groups. Results A significant improvement in NIHSS scores was observed in the treatment group compared to the control group. Additionally, serum levels of SIRT1, HIF-1α, and macrophage efferocytosis-related factors were significantly altered, suggesting that ATET may influence biological pathways involved in stroke recovery. Conclusion The application of ATET, supported by advanced diagnostic technologies, shows promising effects in stroke rehabilitation. This study highlights the potential for integrating traditional therapies with modern medicine to improve clinical outcomes in stroke patients.