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August 6, 2025Hypertension

Time-Restricted Feeding Attenuates Salt-Sensitive Hypertension and Renal Damage

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Authors

LYLauren YunkerMedical College of WisconsinKUKristie UsaMedical College of WisconsinAWAdaysha C. WilliamsEmory University

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Overview

Intervention reduces mean arterial pressure in male salt-sensitive rats on high-salt diet, suggesting alternative management for hypertension.

Key Points

  • Time-restricted feeding significantly attenuated salt-sensitive hypertension in Dahl SS rats on a high-salt diet.
  • Chronic monitoring revealed that TRF blunted further increases in mean arterial pressure during the active phase.
  • Rats subjected to TRF showed reduced sodium excretion and improved creatinine clearance without changing body weight.
  • The findings suggest time-restricted feeding may be a viable alternative to salt-restricted diets for managing hypertension.

Cite This Study

Yunker et al. (2025) studied this question.

synapsesocial.com/papers/689522009f4f1c896c428deahttps://doi.org/10.1161/hypertensionaha.125.24857
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