Pectin-based Bioink and Bioprinting Parameter Optimization and Industrialization

Bioprinting for tissue engineering and regenerative medicine offers a promising solution to the growing demand for organ transplants. A pectin-based bioink was engineered to offer cost-effectiveness and operational simplicity. This project focuses on the commercialization and industrial production of this bioink. The bioink formulation and bioprinting parameters for extrusion-based bioprinting were optimized, as extrusion-based bioprinters are most commonly used in bioprinting. The optimization process focused on structural integrity, resolution, and cell viability. Additionally, an industrial-scale production process was designed using SuperPro Designer. The bioink formulation with optimized bioprinting parameters shows great potential for extrusion-based bioprinting with scalable manufacturing capabilities.