Preoperative Exercise to Improve Fitness in Patients Undergoing Complex Surgery for Cancer of the Lung or Esophagus (PRE-HIIT)

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Randomised trial shows HIIT improves VO2 peak in cancer patients prior to surgery, suggesting enhanced preoperative fitness.

HIIT demonstrated a 6.6% increase in VO2 peak compared to standard care, indicating improved cardiopulmonary fitness.
Participants in the HIIT group increased VO2 peak from 18.7 to 21.7 ml/kg/min, while standard care showed minimal change.
Seventy-nine patients scheduled for lung or esophageal cancer resection were randomly assigned to HIIT or standard care.
These findings suggest that prehabilitation through HIIT can significantly benefit deconditioned patients before major surgery.

Smyth et al. (2025) studied this question.

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