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August 6, 2025International Journal of Molecular SciencesOpen Access

mTOR Signaling in Macrophages: All Depends on the Context

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Authors

AFAngelika FedorKBKrzysztof BryniarskiKNKatarzyna Nazimek

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Overview

Narrative review highlights mTOR signaling's role in macrophages and its implications for autoimmune diseases, implying context matters.

Key Points

  • MAIN FINDING: mTOR signaling in macrophages is context dependent, impacting immune responses and disease processes.
  • KEY EVIDENCE: Deregulation of macrophage activity is linked to various autoimmune diseases, highlighting mTOR's significance.
  • APPROACH: The review synthesizes recent research on mTOR's role in macrophages and its control by microRNAs.
  • SIGNIFICANCE: Understanding mTOR signaling may lead to better therapeutic strategies for autoimmune disorders.

Cite This Study

Fedor et al. (2025) studied this question.

synapsesocial.com/papers/689522129f4f1c896c4298fahttps://doi.org/10.3390/ijms26157598
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