August 5, 2025

Analysis of the Role of Alkaline Phosphatase and Gleason Score in Predicting Prognosis and Risk of Bone Metastasis in Prostate Cancer

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Alkaline phosphatase is a significant independent predictor of bone metastasis in prostate cancer patients.
Bone metastases were found in 58.3% of the prostate cancer patients analyzed in the study.
The study used logistic and ordinal regression analyses to evaluate predictive accuracy of ALP and Gleason score.
ROC curve analysis indicated high diagnostic accuracy for alkaline phosphatase with an AUC of 0.923.

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Implication

Cross-sectional analysis reveals alkaline phosphatase predicts bone metastasis in prostate cancer better than Gleason score, highlighting its prognostic value.

Cite This Study

Putera et al. (2025) studied this question.

synapsesocial.com/papers/689522129f4f1c896c429b3b https://doi.org/10.21203/rs.3.rs-7266645/v1

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Implication

Cross-sectional analysis reveals alkaline phosphatase predicts bone metastasis in prostate cancer better than Gleason score, highlighting its prognostic value.

Analysis of the Role of Alkaline Phosphatase and Gleason Score in Predicting Prognosis and Risk of Bone Metastasis in Prostate Cancer

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Discussion

Implication

Cite This Study

Analysis of the Role of Alkaline Phosphatase and Gleason Score in Predicting Prognosis and Risk of Bone Metastasis in Prostate Cancer

Key Points

Discussion

Implication

Cite This Study

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