August 7, 2025Drugs & AgingOpen Access

Effects of NSAIDs on Early CKD Development: A 10-Year Population-Based Study Using the Korean Senior Cohort

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NSAID use significantly increases the risk of chronic kidney disease (CKD) in senior individuals.
The hazard ratio for CKD associated with NSAID use was found to be 1.46, indicating a notable increase in risk.
Data from 1,812 participants, including 604 NSAID users, were analyzed using Cox regression to evaluate renal function.
Findings suggest that cautious prescription of NSAIDs and regular kidney monitoring are necessary for seniors.

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Population-based study shows NSAID usage raises CKD risk and speeds eGFR decline in older adults, suggesting need for monitoring.

Lim et al. (2025) studied this question.

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