Research demonstrates significant antibacterial activity in a neem cream formulation against acne-causing bacteria, suggesting a safer alternative for treatment.
Acne vulgaris is a common dermatological condition that can be caused by inflammation, bacterial colonization, and sebaceous gland dysfunction. Often, treatment leads to side effects and antibiotic resistance, which necessitates safer alternatives. Azadirachta indica (neem) is a natural remedy due to its antibacterial and anti-inflammatory properties. This study focuses on the formulation and evaluation of a neem-based anti-acne cream. The leaves were harvested, processed into a crude extract and added to a cream base alongside medicinal ingredients such as calendula and zinc oxide. The physical properties and antimicrobial efficacy of the cream were evaluated. Results demonstrated significant inhibition of Propionibacterium acnes and Staphylococcus epidermidis, with inhibition zones comparable to clindamycin. These findings highlight the need for clinical trials to confirm efficacy of neem in dermatological application
No takes yet. Share an insight, caveat, or question.
Khan et al. (2025) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: