Case Report of Autoimmune Hepatitis and Concomitant Primary Biliary Cholangitis

Autoimmune hepatitis with concomitant primary biliary cholangitis has rarely been reported. In this case, we describe a 57-year-old woman who had criteria for this diagnosis based on a liver biopsy that showed a mixed infiltrate of lymphocytes associated with interface hepatitis, rosettes, emperipolesis, plasma cells, and over 50% of the portal ducts did not have a central biliary duct. The treatment provided was Azathioprine, prednisone, and omeprazole, which led to a remarkable complete normalization of her liver enzymes after four weeks. This successful treatment outcome underscores the importance of early identification and treatment for improving long-term outcomes.