Case report highlights elevated CA 125 levels in endometriosis, suggesting possible ovarian cancer, indicating need for careful diagnosis.
Endometriosis is defined as the presence of the endometrial tissue, glands, and stroma, outside the endometrium and myometrium and is characterized by chronic pain and subfertility. Recently, clinical interviews and imaging have increasingly supplemented, and in certain contexts replaced, laparoscopy as the main diagnostic method. However, when we suspect cancer, laparoscopic inspection of abdominal and pelvic cavity, with biopsies and histological confirmation remains the gold standard. The most important biomarker used in endometriosis diagnosis remains CA 125, which is a well established marker in ovarian cancer. The sensitivity of CA 125 limits its clinical usefulness in endometriosis diagnosis. In this paper we present the case of the patient with significantly elevated levels of CA 125 and high suspicion of ovarian neoplasm in imaging studies.
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Kostrzanowski et al. (2025) studied this question.
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