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July 12, 2025Advances in Research

Comparative Effectiveness of Prophylactic Methods for the Prevention of Neonatal Ophthalmia: A Systematic Review

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Authors

RQRoger Antônio Morais QueirozVOValdir Francisco OdorizziTSThaylane Araújo e Silva

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Overview

Systematic review evaluates effectiveness of prophylactic agents in preventing neonatal ophthalmia, indicating povidone-iodine may be preferred for public health use.

Key Points

  • MAIN FINDING: Povidone-iodine 2.5% was identified as the most effective prophylactic agent for neonatal ophthalmia.
  • KEY EVIDENCE: Analysis included 19 studies with 9,287 neonates, showing significant reduction in infectious conjunctivitis rates with povidone-iodine.
  • APPROACH: A systematic review followed PRISMA guidelines, focusing on various topical prophylactic methods against neonatal ophthalmia.
  • SIGNIFICANCE: Povidone-iodine's broad antimicrobial action and low cost suggest its adoption in health protocols is crucial.

Cite This Study

Queiroz et al. (2025) studied this question.

synapsesocial.com/papers/689a02afe6551bb0af8cbed0https://doi.org/10.9734/air/2025/v26i41414
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Neonatal ocular prophylaxis in the United States: is it still necessary?2023 · 12 citations
  2. 2Current Status of Credé Prophylaxis1984
  3. 3Neonatal conjunctivitis: when and how to treat2024
  4. 4Ophthalmic Antibiotic Prophylaxis as a Target for Antibiotic Stewardship: A Point Prevalence Multicentre Survey on Practices, Guideline Adherence, and Incidence of Ophthalmia Neonatorum within the ESPR Network2026
  5. 5Prevalence, Risk Factors, and Microbial Spectrum of Ophthalmia Neonatorum: A Cross-Sectional Study From Central India2026