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July 15, 2025Nutrition ReviewsOpen Access

Clinical Benefits and Safety of Multiple Micronutrient Supplementation During Preconception, Pregnancy, and Lactation: A Review

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Authors

JLJue LiuPeking UniversityKMKonstantinos MantantzisBayer (Germany)LKLigaya KaufmannBayer (Switzerland)

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Implication

Review demonstrates improved health outcomes in mothers and infants with micronutrient supplementation, indicating safety and efficacy during pregnancy and lactation.

Key Points

  • Micronutrient supplementation significantly reduces the risk of neural tube defects and congenital abnormalities during early pregnancy.
  • Trials suggest that MMS improves micronutrient status and maternal health, enhancing reproductive conditions before and during pregnancy.
  • Very few adverse events related to MMS were reported in infants, underscoring its safety during lactation.
  • Using 800 μg of folic acid in MMS is shown to be more effective than 400 μg alone in supporting healthy pregnancy outcomes.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/689a02b6e6551bb0af8cc4a5https://doi.org/10.1093/nutrit/nuaf079
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