July 15, 2025Open Access

Building Trust for Improving Vaccine Uptake: An Integrative Review of COVID-19 Vaccine Hesitancy in the Global North and South

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Vaccine hesitancy is a notable global challenge affecting both the Global North and South.
Distrust in pharmaceutical companies and government agencies largely drives vaccine hesitancy.
Psychological and social predictors of vaccine refusal are often overlooked but crucial for understanding hesitancy.
The proposed conceptual model aims to guide policymakers in addressing vaccine compliance through trust-building.

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Integrative review reveals psychological and social factors affect vaccine uptake globally, indicating need for targeted public health strategies.

Ndoye et al. (2025) studied this question.

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Integrative review reveals psychological and social factors affect vaccine uptake globally, indicating need for targeted public health strategies.