Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 15, 2025World Journal of DiabetesOpen Access

Pharmacological management of type 2 diabetes mellitus in children and adolescents: A systematic review and network meta-analysis

View Full Paper
Ask AI
Bookmark
Share

Authors

CGCharles A GagnonKBKatherine L. BuchananJDJ. MONTGOMERY DEAVER

Discussion

Loading...

Member takes

Overview

Network meta-analysis shows dulaglutide and dapagliflozin significantly lower HbA1c in children, indicating the need for more robust trials.

Key Points

  • MAIN FINDING: Dulaglutide, dapagliflozin, and liraglutide effectively reduce HbA1c levels in children with type 2 diabetes.
  • KEY EVIDENCE: HbA1c decreased by 1.20 for dulaglutide and 0.94 for dapagliflozin compared to control.
  • APPROACH: Analyzed data from 12 RCTs involving 1658 participants, assessing various pharmacological treatments.
  • SIGNIFICANCE: Results highlight potential effective treatments for managing type 2 diabetes in a pediatric population.

Cite This Study

Gagnon et al. (2025) studied this question.

synapsesocial.com/papers/689a02b6e6551bb0af8cc551https://doi.org/10.4239/wjd.v16.i7.106890
View Full Paper
Ask AI
Bookmark
Share