July 15, 2025

Supplemental Figure 7 from Integration of Germline and Somatic Variation Improves Chronic Lymphocytic Leukemia Risk Stratification

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Model calibration improves risk estimation in chronic lymphocytic leukemia, suggesting enhanced stratification methods for better outcomes.

Integration of germline and somatic variation leads to improved risk stratification in chronic lymphocytic leukemia.
The model utilizes a 30% UK Biobank testing set for effective validation of results.
Calibration on a relative risk scale enhances the accuracy of predicted outcomes for patients.
Improving risk assessment can lead to better treatment strategies and patient management in chronic lymphocytic leukemia.

Hubbard et al. (2025) studied this question.

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Model calibration improves risk estimation in chronic lymphocytic leukemia, suggesting enhanced stratification methods for better outcomes.