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July 16, 2025HealthcareOpen Access

The Adjunctive Role of Antimicrobial Photodynamic Therapy to Non-Surgical Treatment in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

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Authors

APAlessia PardoASAnnarita SignorielloEMElena Messina

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Overview

Systematic review highlights improved clinical outcomes in T2DM patients undergoing adjunctive antimicrobial photodynamic therapy during non-surgical treatment.

Key Points

  • Adjunctive antimicrobial photodynamic therapy significantly reduces bleeding on probing in T2DM patients after treatment.
  • Probing pocket depth improved substantially in T2DM patients receiving combined therapy compared to NSPT alone.
  • Meta-analysis included 15 studies assessing the efficacy of aPDT alongside typical periodontal treatment.
  • This combined therapy offers a promising approach for managing periodontitis in individuals with type 2 diabetes mellitus.

Cite This Study

Pardo et al. (2025) studied this question.

synapsesocial.com/papers/689a02c3e6551bb0af8cc9abhttps://doi.org/10.3390/healthcare13141703
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of Safety and Efficacy of Glaritus® versus Lantus® in Combination with Insulin Lispro among Adults with Type 1 Diabetes Mellitus-Phase IV Study2017 · 4 citations
  2. 2The Pathobiology of Diabetic Complications2005 · 5,356 citations
  3. 3The effect of antimicrobial photodynamic therapy on periodontal disease and glycemic control in patients with type 2 diabetes mellitus2023 · 21 citations