Contemporary antiarrhythmic pharmacotherapy: revisiting the Old, exploring the New

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Atrial fibrillation affects about 2% of the general population with rising rates in older adults.
Current arrhythmia management primarily relies on antiarrhythmic drugs despite limitations in safety and efficacy.
Emerging therapies and pharmacological targets offer the potential to enhance arrhythmia treatment.
Innovative drug therapies could significantly change the future landscape of antiarrhythmic pharmacotherapy.

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Review highlights antiarrhythmic drugs and emerging pharmacological targets for arrhythmias, suggesting future treatment innovations.

Totolici et al. (2025) studied this question.

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