Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 16, 2025

Outcomes in relapsed/refractory diffuse large B-cell lymphoma in an Asian tertiary cancer center: contemporary interventions as a benchmark for novel therapy

View Full Paper
Ask AI
Bookmark
Share

Authors

JCJason Yongsheng ChanNLNicole-Ann LimYSYining Sun

Discussion

Loading...

Member takes

Overview

Retrospective cohort study assesses survival outcomes in relapsed refractory diffuse large B-cell lymphoma, highlighting the need for improved therapies.

Key Points

  • Patients with primary refractory diffuse large B-cell lymphoma had a median progression-free survival of 2.2 months.
  • Among 227 patients, 76.7% were diagnosed at advanced stages (Ann Arbor III-IV).
  • Transplant recipients showed significantly better overall survival compared to non-recipients, with a hazard ratio of 2.93.
  • Novel therapeutics like CAR-T and bispecifics may enhance treatment outcomes for these challenging cases.

Cite This Study

Chan et al. (2025) studied this question.

synapsesocial.com/papers/689a02c3e6551bb0af8cca41https://doi.org/10.21203/rs.3.rs-7108890/v1
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Real life clinical outcomes of relapsed/refractory diffuse large B cell lymphoma in the rituximab era: The <scp>STRIDER</scp> study2024 · 12 citations
  2. 2Real-world Outcomes of Diffuse Large B-cell Lymphoma Treated with frontline R-CHOP(-like) regimens in an Asian Multi-ethnic Population2024
  3. 3Real-world outcomes with novel therapies in relapsed/refractory diffuse large B-cell lymphoma2024 · 1 citations
  4. 4Real‐world patient characteristics, treatment patterns, and treatment outcomes of patients with diffuse large B‐cell lymphoma by line of therapy2024 · 18 citations
  5. 5Outcomes and prognostic factors of patients diagnosed with relapsed/refractory primary B-cell lymphoma: A retrospective study.2024 · 1 citations