July 16, 2025Open Access

Neuron-Microenvironments Associated with Specific Long-Range Connectivity Reveal Functional Modules in the Adult Drosophila Brain

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Discussion

Analysis improves spatial coherence of microenvironment features in Drosophila brain, suggesting roles in communication and processing.

Neurons in Drosophila are categorized by polarity, leading to refined brain region distinctions.
Microenvironment features enhanced spatial coherence by 68%, showing their importance for structural understanding.
Integration of EM and scRNA-seq data illustrates links to transmembrane transport and metabolism for intercellular communications.
Clustering distal projections reveals functional modules associated with feeding and multisensory processing.

Hanchuan Peng (2025) studied this question.

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