July 19, 2025BMC Oral HealthOpen Access

Silver diamine fluoride: the science behind the action – a narrative review

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Narrative review explores silver diamine fluoride’s mechanism of action in caries treatment, suggesting formulation standardization is crucial.

Silver diamine fluoride is effective in managing caries, but its mechanism of action remains unclear.
The review analyzed 40 studies highlighting variations in silver, fluoride, and pH affecting SDF performance.
Understanding SDF's antimicrobial and remineralization properties is essential for better clinical outcomes.
There is a notable need for standardization in SDF formulations to ensure consistent therapeutic results.

Jamal et al. (2025) studied this question.

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Narrative review explores silver diamine fluoride’s mechanism of action in caries treatment, suggesting formulation standardization is crucial.