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July 21, 2025Open Access

CMV in Pregnancy: Effects on the Developing Embryo and Fetus, Diagnosis and Treatment. Where to Go Now?

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Authors

AOAsher OrnoyMorpho (United States)LWLiza Weinstein‐FudimHebrew University of Jerusalem

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Implication

Findings show fetal infection from cytomegalovirus linked to maternal health, indicating urgent need for screening and treatment.

Key Points

  • Cytomegalovirus is the leading teratogenic virus affecting fetal development, particularly during the first trimester.
  • Primary maternal infection increases the risk of fetal infection, potentially leading to hearing loss and neurological deficits.
  • Treatment with valacyclovir may reduce severity of fetal infection, while ganciclovir can limit postnatal hearing loss progression.
  • Screening recommendations for pregnant women and newborns have been updated to address the impacts of cytomegalovirus.

Cite This Study

Ornoy et al. (2025) studied this question.

synapsesocial.com/papers/689a02c9e6551bb0af8cd08ehttps://doi.org/10.20944/preprints202507.1510.v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Congenital Cytomegalovirus Infection: From Silent Threat to Vaccine Horizon2025 · 2 citations
  2. 2Prenatal and postnatal antiviral therapies for the prevention and treatment of congenital cytomegalovirus infections2024 · 7 citations
  3. 3Prenatal Diagnosis and Postnatal Outcomes in a Case of Primary Maternal Cytomegalovirus Infection2025
  4. 4Maternal and Congenital cytomegalovirus (cCMV) - A Review article2025
  5. 5Antenatal treatment options for primary cytomegalovirus infections2018 · 13 citations