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July 21, 2025Expert Review of Pharmacoeconomics & Outcomes Research

Cost effectiveness of non-pharmacological interventions for fatigue in patients with long-term conditions: a systematic literature review

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Authors

SDSarah DavisMMMon Mon-YeeASAnthea Sutton

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Overview

Systematic review assesses cost-effectiveness of non-pharmacological interventions for fatigue in chronic conditions, indicating potential savings for healthcare systems.

Key Points

  • MAIN FINDING: Non-pharmacological interventions for fatigue showed varying cost-effectiveness in patients with chronic conditions.
  • KEY EVIDENCE: Cognitive behavioral therapy had an incremental cost-effectiveness ratio over £30,000, while personalized exercise program presented greater cost benefits.
  • APPROACH: This systematic review included studies on fatigue treatments and used a two-stage sifting process to select relevant research articles.
  • SIGNIFICANCE: Cost-effective interventions could significantly improve patient care while reducing financial burdens on healthcare systems.

Cite This Study

Davis et al. (2025) studied this question.

synapsesocial.com/papers/689a060ee6551bb0af8cd236https://doi.org/10.1080/14737167.2025.2537194
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cost-effectiveness of interventions for medically unexplained symptoms: A systematic review2018 · 45 citations
  2. 2Non-pharmacological interventions for fatigue in rheumatoid arthritis2013 · 223 citations
  3. 3A pragmatic parallel arm multi-centre randomised controlled trial to assess the effectiveness and cost-effectiveness of a group-based fatigue management programme (FACETS) for people with multiple sclerosis2013 · 149 citations
  4. 4Most patients who reach disease remission following anti-TNF therapy continue to report fatigue: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis2016 · 103 citations