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July 22, 2025Open Access

Effects of Parietal Cathodal tDCS during Game Cue Exposure on Internet Gaming Disorder: A Randomized Double-Blind Sham-Controlled Trial

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Authors

YSYixuan SongYHYuchen HuangQZQiping Zheng

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Overview

Randomized trial reduced craving and gaming time in participants with Internet Gaming Disorder, suggesting tDCS may be an effective treatment.

Key Points

  • MAIN FINDING: Targeting parieto-occipital P300 using cathodal tDCS reduced craving in participants with internet gaming disorder.
  • KEY EVIDENCE: Active tDCS led to significant reductions in gaming time and craving scores (p < 0.001) during cue exposure.
  • APPROACH: Randomized, double-blind trial with 46 IGD participants comparing active versus sham tDCS during game cues.
  • SIGNIFICANCE: This research supports the use of neuromodulation and EEG biomarkers in treating behavioral addictions like IGD.

Cite This Study

Song et al. (2025) studied this question.

synapsesocial.com/papers/689a0614e6551bb0af8cd6dbhttps://doi.org/10.1101/2025.07.20.25331859
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The P300: Where in the Brain Is It Produced and What Does It Tell Us?2005 · 852 citations
  2. 2On the ability to inhibit thought and action: General and special theories of an act of control.2014 · 883 citations
  3. 3Efficacy of single-session transcranial direct current stimulation on addiction-related inhibitory control and craving: a randomized trial in males with Internet gaming disorder2021 · 60 citations
  4. 4Effectiveness of Cognitive Behavioral Therapy–Based Intervention in Preventing Gaming Disorder and Unspecified Internet Use Disorder in Adolescents2022 · 148 citations
  5. 5Frontal tDCS reduces alcohol relapse rates by increasing connections from left dorsolateral prefrontal cortex to addiction networks2023 · 27 citations