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July 22, 2025Frontiers in PharmacologyOpen Access

Corticosteroid-induced manic and/or psychotic symptoms: a systematic review

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Authors

SGSara GostoliDCDanilo CarrozzinoGRGiulia Raimondi

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Overview

Systematic review examines corticosteroid-induced manic and psychotic symptoms in patients, highlighting risk factors for their development.

Key Points

  • Corticosteroids can induce both manic and psychotic symptoms in patients, affecting 64.7% of clinical cases reviewed.
  • High-dose corticosteroids and pre-existing psychiatric conditions are significant risk factors for developing these symptoms.
  • The systematic review analyzed 40 papers, including 34 clinical cases and 6 quantitative studies on corticosteroid impacts.
  • Identifying and assessing corticosteroid-induced symptoms remains challenging, necessitating improved early detection methods.

Cite This Study

Gostoli et al. (2025) studied this question.

synapsesocial.com/papers/689a0614e6551bb0af8cd6f9https://doi.org/10.3389/fphar.2025.1628765
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