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July 22, 2025DiabetologiaOpen Access

Heterogeneity in the development of diabetes-related complications: narrative review of the roles of ancestry and geographical determinants

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Authors

ALAndrea O. Y. LukYFYingnan FanBFBaoqi Fan

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Overview

Narrative review examines diabetes-related complications across ethnic groups, suggesting socioeconomic position and geographical determinants play significant roles.

Key Points

  • Diabetes-related complications vary widely among ethnic groups, with Black and South Asian individuals showing higher risk for conditions like chronic kidney disease and stroke.
  • Incidence of complications is generally lower in high-income countries, indicating the influence of geographical determinants on health outcomes.
  • Socioeconomic position and education level significantly impact the incidence of diabetes-related complications, often overshadowing biological factors.
  • International migration can alter disease trajectories, highlighting how environmental changes can affect the health of individuals with diabetes.

Cite This Study

Luk et al. (2025) studied this question.

synapsesocial.com/papers/689a061be6551bb0af8cd8fehttps://doi.org/10.1007/s00125-025-06482-8
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Race, ethnicity and ancestry in global diabetes research: grappling with complexity to advance equity and scientific integrity – a narrative review and viewpoint2025
  2. 2Type 2 diabetes complications in ethnic minority compared with European host populations: a systematic review and meta-analysis2024 · 9 citations
  3. 3Racial/ethnic inequities in diabetes mellitus: a narrative review2026
  4. 4Does ethnic origin have an independent impact on hypertension and diabetic complications?2005 · 52 citations
  5. 5Cardiovascular disease and diabetes in patients with African or Asian background2017 · 11 citations