Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 23, 2025CellsOpen Access

Nanotechnology-Based Delivery of CRISPR/Cas9 for Cancer Treatment: A Comprehensive Review

View Full Paper
Ask AI
Bookmark
Share

Authors

MRMohd Ahmar RaufAligarh Muslim UniversityARA.K.S.Bhujanga RaoJamia HamdardSSSiva Sankari SivasoorianWayne State University

Discussion

Loading...

Member takes

Implication

This review highlights innovative nanotechnology approaches for improving in vivo delivery of CRISPR/Cas9 in cancer, suggesting potential advancements in gene editing and immunotherapy.

Key Points

  • CRISPR/Cas9 is a powerful tool for cancer gene editing, capable of targeting genetic modifications.
  • Nanocarriers enhance the in vivo delivery of CRISPR/Cas9, improving tumor localization and minimizing off-target effects.
  • Optimizing nanocarrier properties such as size and composition is key to effective gene editing.
  • Innovative strategies in nanotechnology can advance the clinical application of CRISPR/Cas9 in cancer therapy.

Cite This Study

Rauf et al. (2025) studied this question.

synapsesocial.com/papers/689a0621e6551bb0af8cdd6chttps://doi.org/10.3390/cells14151136
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Basic Guide for Approaching Drug Delivery with Extracellular Vesicles2024 · 8 citations
  2. 2The advancements and prospective developments in anti-tumor targeted therapy2024 · 38 citations
  3. 3Focused ultrasound gene delivery for the treatment of neurological disorders2024 · 41 citations
  4. 4Fast and Efficient CRISPR/Cas9 Genome Editing In Vivo Enabled by Bioreducible Lipid and Messenger RNA Nanoparticles2019 · 374 citations
  5. 5Development and Brain Delivery of Chitosan−PEG Nanoparticles Functionalized with the Monoclonal Antibody OX262005 · 319 citations