Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 25, 2025Current Issues in Molecular BiologyOpen Access

Molecular Mechanisms of Radiation Resistance in Breast Cancer: A Systematic Review of Radiosensitization Strategies

View Full Paper
Ask AI
Bookmark
Share

Authors

EMEmma MageauLaurentian UniversityRDRonan DerbowkaSaskatchewan Cancer AgencyNDNoah DickinsonLaurentian University

Discussion

Loading...

Member takes

Overview

Systematic review identifies radiation resistance mechanisms in breast cancer, suggesting targets for radiosensitization strategies.

Key Points

  • Breast cancer is often resistant to radiation therapy, impacting treatment effectiveness.
  • Key mechanisms affecting radiation resistance include DNA damage repair and dysregulated signaling pathways.
  • Non-coding RNAs and tumor microenvironment factors also play roles in modulating radiation response.
  • Identifying these mechanisms offers new strategies for improving radiosensitivity and treatment outcomes.

Cite This Study

Mageau et al. (2025) studied this question.

synapsesocial.com/papers/689a0627e6551bb0af8ce096https://doi.org/10.3390/cimb47080589
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Innovative therapeutic strategies to overcome radioresistance in breast cancer2024 · 3 citations
  2. 2Current Perspectives on Radiosensitizers in Cancer Radiotherapy2026 · 4 citations
  3. 3Molecular Biomarkers of Radiosensitivity and Radioresistance in Cervical Cancer: A Systematic Review2026
  4. 4Non‐Coding <scp>RNAs</scp> in Breast Cancer Radioresistance: Mechanisms, Functional Roles and Translational Potentials2025
  5. 5Nanoparticle-Mediated Radiosensitization in Breast Cancer: A Systematic Review of Preclinical Evidence and Translational Challenges2026