July 25, 2025World Journal of Stem Cells

Regulation and intervention of stem cell differentiation by long non-coding RNAs: Mechanisms and therapeutic potential

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Long non-coding RNAs are essential for regulating gene expression and maintaining stem cell pluripotency.
These RNAs influence stem cell fate decisions through epigenetic, transcriptional, and post-transcriptional mechanisms.
Research emphasizes the therapeutic potential of lncRNA-based strategies for regenerative medicine and targeted therapies.
Challenges and future directions in lncRNA research are discussed to advance the field of stem cell therapy.

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Implication

This review demonstrates how long non-coding RNAs regulate differentiation in stem cells, highlighting their therapeutic potential in regenerative medicine and disease modeling.

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Li et al. (2025) studied this question.

synapsesocial.com/papers/689a0627e6551bb0af8ce19c https://doi.org/10.4252/wjsc.v17.i7.107688

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Implication

This review demonstrates how long non-coding RNAs regulate differentiation in stem cells, highlighting their therapeutic potential in regenerative medicine and disease modeling.

Regulation and intervention of stem cell differentiation by long non-coding RNAs: Mechanisms and therapeutic potential

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Discussion

Implication

Cite This Study

Regulation and intervention of stem cell differentiation by long non-coding RNAs: Mechanisms and therapeutic potential

Key Points

Discussion

Implication

Cite This Study

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