July 25, 2025Open Access

Microrheological and Microfluidic Approaches for Evaluation the Mechanical Properties of Blood Cells

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Main finding highlights the potential of erythrocyte deformability as a biomarker for diabetes and cancer.
Evidence shows hemorheological alterations, like increased blood viscosity and RBC aggregation, affect microcirculation.
Approach includes microfluidic platforms for in vitro assays of blood cell mechanics and aggregation.
Significance lies in improving diagnostics and understanding microvascular complications in various diseases.

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This review reveals advances in microfluidic methods for analyzing erythrocyte and leukocyte mechanics, indicating their role in disease diagnostics.

Антонова et al. (2025) studied this question.

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This review reveals advances in microfluidic methods for analyzing erythrocyte and leukocyte mechanics, indicating their role in disease diagnostics.