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July 27, 2025

Risk Factors for Mortality in Children with Hypoxemia in Resource- Constrained Settings: A Secondary Analysis of the Global PARITY Study

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Authors

CBCarter BiewenSWShan L. WardAAAsya Agulnik

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Overview

Secondary analysis reveals higher mortality associated with hypoxemia in children, indicating the importance of respiratory care resources.

Key Points

  • Children with hypoxemia in resource-constrained settings faced a 6.8% mortality rate, underscoring the impact of limited medical resources.
  • Seventy percent of hypoxemic children were treated at hospitals with intermediate or less respiratory care resources available.
  • Logistic regression analysis found that mortality odds were significantly higher for those treated at sites with inadequate respiratory care resources.
  • The presence of a PARDS trigger did not correlate with mortality, highlighting complexities in diagnosing pediatric acute respiratory distress syndrome.

Cite This Study

Biewen et al. (2025) studied this question.

synapsesocial.com/papers/689a0939e6551bb0af8ce7a1https://doi.org/10.21203/rs.3.rs-7143199/v1
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Also Consider

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  3. 3Hypoxaemia and mortality in children with lower respiratory infection in low-income and middle-income countries: systematic review and meta-analysis2026
  4. 4Nutritional Status and Mechanical Ventilation Practices in Pediatric Acute Respiratory Distress Syndrome: A Secondary Analysis of the 2017–2023 PARDSAsia Study2025
  5. 5Predictors of Outcomes in Pediatric Acute Respiratory Distress Syndrome at a Tertiary Care Hospital2026