Factors Associated With Noncompliance With the Prenatal Vaccination Schedule Among Pregnant Women in Kamina, DRC

BACKGROUND: Vaccination is a key strategy for reducing maternal and neonatal morbidity and mortality. However, adherence to antenatal vaccination remains insufficient in many resource-limited areas. This study aimed to identify factors associated with nonadherence to vaccination schedules among pregnant women in Kamina, DRC. METHODS: This analytical cross-sectional study was conducted between January and July 2025 among 422 pregnant women attending antenatal clinics. Data were collected via a structured questionnaire, administered face-to-face, and analyzed via SPSS 26 and Jamovi 2.5.5 software. Multivariate logistic regression was used to identify factors associated with noncompliance with the vaccination schedule. RESULTS: The prevalence of noncompliance with the vaccination schedule was 63.7%. The factors significantly associated with noncompliance were being married (ORa = 7.116; 95% CI [3.963-12.776]), a lack of education (ORa = 4.121; 95% CI [2.422-7.012]), the presence of natural obstacles to the health center (ORa = 4.833; 95% CI [2.089-11.184]) and the perception of a long waiting time (ORa = 3.734; 95% CI [2.251-6.194]). CONCLUSION: The results highlight sociodemographic, geographic, and health care delivery factors influencing vaccination adherence. Targeted, community-based, and multisectoral interventions are needed to improve antenatal vaccination coverage in this setting.