July 29, 2025NeuropsychopharmacologyOpen Access

Understanding the emergence of suicidal thoughts and behaviors in adolescence from a brain and behavioral developmental perspective

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This review highlights how brain changes affect suicidal thoughts in adolescents, suggesting targeted interventions may reduce risks.

Suicidal thoughts and behaviors are common in adolescents and linked to significant brain changes during this period.
Neuroimaging studies identify key brain areas implicated in emotion regulation and impulse control in youth with suicidal tendencies.
Targeted psychotherapeutic and neuromodulatory interventions can effectively influence brain processes related to suicidal behavior.
Understanding neural trajectories in adolescents is crucial for developing improved assessment and treatment strategies for at-risk youth.

Lewis et al. (2025) studied this question.

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