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July 29, 2025BMC Musculoskeletal DisordersOpen Access

Risk factors of residual back pain after vertebral augmentation in osteoporotic vertebral compression fracture patients: a systematic review and meta-analysis

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Authors

HWHaozhong WangHarbin Institute of TechnologyHZHao ZhangNorthwestern Polytechnical UniversityCXChangming XiaoSouthwest Medical University

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Overview

This meta-analysis reveals significant risk factors for residual back pain in patients with osteoporotic vertebral compression fractures, suggesting targeted preventive measures.

Key Points

  • MAIN FINDING: Lower bone mineral density (BMD), lower BMI, and depression significantly contribute to residual back pain after vertebral augmentation.
  • KEY EVIDENCE: Patients with severe paraspinal muscle degeneration showed an OR of 6.25 for experiencing residual back pain post-surgery.
  • APPROACH: Meta-analysis included data from 11 studies, assessing 12 risk factors in 3290 patients undergoing vertebral augmentation.
  • SIGNIFICANCE: Identifying these risk factors can guide early interventions, potentially reducing the incidence of residual back pain in patients.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/689a093fe6551bb0af8cec27https://doi.org/10.1186/s12891-025-08945-w
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