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July 29, 2025npj Biofilms and MicrobiomesOpen Access

Gut microbiota shapes cancer immunotherapy responses

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Authors

WLWanting LeiKZKexun ZhouYLYe Lei

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Overview

This review highlights how gut microbiota affects immune responses in cancer treatments, suggesting microbiota-based strategies may enhance immunotherapy.

Key Points

  • Gut microbiota plays a crucial role in determining the success of cancer immunotherapy treatments.
  • Clinical and preclinical studies indicate that microbiota-based strategies improve immune response and treatment efficacy.
  • Interventions such as FMT and probiotics show promise in reducing adverse immune-related events during therapy.
  • Advancing microbiota-focused therapies could refine precision immunotherapy approaches for cancer patients.

Cite This Study

Lei et al. (2025) studied this question.

synapsesocial.com/papers/689a093fe6551bb0af8cec2dhttps://doi.org/10.1038/s41522-025-00786-8
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Also Consider

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  5. 5The gut microbiota in cancer immunity and immunotherapy2025 · 97 citations