July 29, 2025

A retrospective review of histopathological findings after cholecystectomy in a single center in Palestine

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Discussion

Retrospective review shows low incidence of gallbladder carcinoma in 2371 patients, suggesting selective histopathological examination.

The study indicates that the rate of pre-malignant and malignant gallbladder lesions post-cholecystectomy is very low.
Chronic cholecystitis was found in 82.5% of the specimens, while adenocarcinoma appeared in less than 0.1%.
A total of 2371 patients underwent cholecystectomy with laparoscopic procedures accounting for 84.6% of cases.
Routine histopathological examination may not be necessary without clinical suspicion, advocating for a more selective approach.

Darawsha et al. (2025) studied this question.

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