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July 30, 2025Journal of Clinical MedicineOpen Access

Impact of Perioperative Antibiotic Prophylaxis in Caesarean Section on the Maternal Gut Microbiome: A Systematic Review

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Authors

EFElisabeth FelesCNClaudio NeidhöferCWChristina Wessels

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Overview

Systematic review reveals antibiotic prophylaxis alters maternal gut microbiome, highlighting variability in outcomes and the need for further studies.

Key Points

  • Maternal gut microbiome may be disrupted by antibiotic prophylaxis in caesarean section, impacting recovery.
  • Review analyzed three studies involving 286 mothers, all showing inconsistent microbiome outcomes post-antibiotic exposure.
  • Current literature relies on diverse methodologies which limit comparability of microbiome metrics like alpha and beta diversity.
  • Understanding the maternal gut microbiome is crucial for neonatal health and warrants further focused research.

Cite This Study

Feles et al. (2025) studied this question.

synapsesocial.com/papers/689a0945e6551bb0af8ceea4https://doi.org/10.3390/jcm14145104
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