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July 31, 2025

Effect of Omega-3 Supplementation vs. Placebo on Blood Lipid Levels in Patients with Ischemic Heart Disease: A Systematic Review and Meta-Analysis

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Authors

ANAhmed NegmMayo ClinicAAAhmed M. AshourAin Shams UniversityMMMazin MohamedSouth Valley University

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Implication

Systematic review shows omega-3 significantly reduces triglycerides and LDL-C in patients with ischemic heart disease, suggesting potential as adjunct therapy.

Key Points

  • Omega-3 supplementation effectively reduces triglycerides by 17.53 mg/dL in patients with ischemic heart disease.
  • LDL-C levels decreased by 9.43 mg/dL after omega-3 supplementation, indicating a positive effect on lipid profiles.
  • Data was derived from 10 randomized controlled trials involving 633 patients with established criteria for ischemic heart disease.
  • Finding supports omega-3 as a potential treatment for managing dyslipidemia in ischemic heart disease, emphasizing the need for further research.

Cite This Study

Negm et al. (2025) studied this question.

synapsesocial.com/papers/689a094be6551bb0af8cf3a1https://doi.org/10.21203/rs.3.rs-6408149/v1
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