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July 31, 2025PeerJOpen Access

The role of mast cells in allergic rhinitis

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Authors

JZJin ZhangXXXiaofei XieRMRuixia Ma

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Overview

Review demonstrates mast cells influence inflammatory responses in allergic rhinitis, suggesting new therapeutic approaches.

Key Points

  • Mast cells play a central role in allergic rhinitis, orchestrating inflammation and airway contraction.
  • Histamine and bioactive lipids are key mediators released by mast cells during allergic reactions.
  • Activation of mast cells in allergic rhinitis occurs via specific IgE receptors and other stimuli.
  • Understanding mast cells can lead to improved treatment for allergic rhinitis in patients.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/689a094be6551bb0af8cf3c5https://doi.org/10.7717/peerj.19734
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