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July 31, 2025Journal of Medical SciencesOpen Access

Beyond Lactate: The Evolving Landscape of Biomarkers for Sepsis in Critical Care – A Systematic Review and Critical Analysis

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Authors

SSShibu Sasidharan

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Overview

Systematic review evaluates diagnostic and prognostic value of sepsis biomarkers in ICU, indicating challenges and future directions.

Key Points

  • Combining established and novel biomarkers may improve sepsis management in ICU settings.
  • Review analyzed 45 studies on 23 biomarkers, notably procalcitonin and C-reactive protein.
  • Emerging biomarkers show potential for better diagnosis but require further validation.
  • Integration of biomarkers into clinical decision support systems could enhance sepsis outcomes.

Cite This Study

Shibu Sasidharan (2025) studied this question.

synapsesocial.com/papers/689a0c5fe6551bb0af8cf64ehttps://doi.org/10.4103/jmedsci.jmedsci_49_25
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  1. 1The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)2016 · 29,056 citations
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