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July 31, 2025BMC AnesthesiologyOpen Access

Intraoperative hypotension prediction in cardiac and noncardiac procedures: is HPI truly worthwhile? A systematic review and meta-analysis

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Authors

ESErfan ShirmohamadiRDReza Hosseini DolamaNMNarjes Mohammadzadeh

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Overview

Systematic review evaluates HPI's ability to predict intraoperative hypotension in cardiac and non-cardiac surgeries, suggesting its clinical advantage remains uncertain.

Key Points

  • The Hypotension Prediction Index (HPI) shows high sensitivity and specificity (83%) in predicting intraoperative hypotension.
  • Meta-analysis of 22 studies indicates the pooled area under the curve (AUC) for HPI is 0.90.
  • Subgroup analysis reveals variability in HPI performance, especially lower odds ratios in cardiac procedures.
  • While HPI may reduce hypotension duration, its impact on cardiovascular or renal outcomes requires further investigation.

Cite This Study

Shirmohamadi et al. (2025) studied this question.

synapsesocial.com/papers/689a0c5fe6551bb0af8cf821https://doi.org/10.1186/s12871-025-03250-4
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Intraoperative Hypotension Prediction—A Proactive Perioperative Hemodynamic Management—A Literature Review2023 · 17 citations
  2. 2Hypotension Prediction Index and Incidence of Perioperative Hypotension: A Single-Center Propensity-Score-Matched Analysis2023 · 14 citations
  3. 3Discrimination and calibration properties of the hypotension probability indicator during cardiac and vascular surgery2019 · 48 citations
  4. 4Intraoperative hypotension and its prediction2019 · 47 citations
  5. 5CON: The hypotension prediction index is not a validated predictor of hypotension2023 · 25 citations