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August 1, 2025Open Access

Changes in Serum Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Their Relationship with Kidney Function in Different Stages of Chronic Kidney Disease

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Authors

BIBorislav IgnatovKKKrasimir KostovTETsvetelina Eftimova

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Overview

This study finds elevated NGAL levels correlated with kidney function decline in CKD patients, suggesting its potential as an important biomarker.

Key Points

  • NGAL levels rise significantly as chronic kidney disease progresses, reflecting worsening kidney function.
  • There is a strong correlation between increased NGAL levels and lower estimated glomerular filtration rate (eGFR).
  • Patients were categorized into three CKD groups based on eGFR levels for thorough analysis of NGAL.
  • Using NGAL as a biomarker could enhance existing diagnosis and monitoring methods for chronic kidney disease.

Cite This Study

Ignatov et al. (2025) studied this question.

synapsesocial.com/papers/689a0c65e6551bb0af8cfadbhttps://doi.org/10.20944/preprints202507.2290.v1
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