⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

August 1, 2025

Supplementary Figure S4 from Highly Sensitive DNA Testing of Fusobacterium nucleatum in Colorectal Tumors

Meredith A.J. Hullar Orsalem J. Kahsai Courtney M. Hill Lisa Levy Rachel C. Malen Keith R. Curtis Hamza Ammar Arthur Sillah Adriana M. Reedy Johanna W. Lampe Shuji Ogino John D. Potter Polly A. Newcomb Amanda I. Phipps

View at Publisher

Ask AI

Bookmark

Share

Key Points

MAIN FINDING: The study focuses on detecting fusobacterium nucleatum in colorectal tumors through sensitive DNA testing.
KEY EVIDENCE: Serial dilution of nusG template shows consistent detection across varying concentrations using the qPCR method.
APPROACH: The linearity of detection was assessed with a quantitative PCR system applied to coli tumor samples.
SIGNIFICANCE: This technique may enhance early detection strategies for colorectal cancer, improving patient outcomes.

Implication

Detection method assesses linearity of Fusobacterium nucleatum templates through qPCR, indicating its potential in colorectal cancer diagnostics.

Abstract

Supplementary Figure S4: Detection of a serial dilution of nusG template using qPCR systems for the assessment of linearity.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Hullar et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d00f6 https://doi.org/10.1158/1055-9965.29762037

View at Publisher

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S5 from Highly Sensitive DNA Testing of <i>Fusobacterium nucleatum</i> in Colorectal Tumors2025
2Supplementary Figure S3 from Highly Sensitive DNA Testing of <i>Fusobacterium nucleatum</i> in Colorectal Tumors2025
3Supplementary Figure S2 from Highly Sensitive DNA Testing of <i>Fusobacterium nucleatum</i> in Colorectal Tumors2025
4Supplementary Figure S1 from Highly Sensitive DNA Testing of <i>Fusobacterium nucleatum</i> in Colorectal Tumors2025
5Data from Highly Sensitive DNA Testing of <i>Fusobacterium nucleatum</i> in Colorectal Tumors2025

Quantification of Ectopic Fusobacterium Colonisation in Colorectal Cancer Using a Newly Developed nusG-Directed PCR Method2026
A Duplex qPCR Assay Targeting the fadA Gene Enables Robust Detection of Fusobacterium in Clinical Samples2025
Figure S1 from Next-generation Multi-target Stool DNA Panel Accurately Detects Colorectal Cancer and Advanced Precancerous Lesions2024